Reactivating ARTIUM’s Collection

Reactivating Memories for Consolidation

The consolidation of memory is thought to occur via a hippocampal-neocortical dialog involving reactivation of memory patterns in the hippocampus during sharp-wave ripples. In this issue of Neuron, Nakashiba et al. demonstrate that CA3 output is required for consolidation of contextual fear memory. They also show that lack of CA3 output results in a decrease in ripple-related reactivation, prov...

Memory retrieval: Reactivating sensory cortex

Associating information with vivid sensory cues aids recall of that information. New experiments help shed some light on the brain mechanisms of memory retrieval that make this mnemonic technique so effective.

Stability monitoring of some acetylcholinesterase reactivating drugs

Background Widespread use of organophosphorous compounds (OPs) in agriculture and as nerve agents as well as a lack of clinically effective antidotes initiated the synthesis of new pyridinium bis-aldoximes (K-compounds) with high potency in reactivating acetylcholinesterase irreversibly inhibited by OPs [1,2]. We aimed to optimize an HPLC method sensitive enough to determine K-compounds from di...

Reactivating nuclear PTEN to treat CLL

Reactivating a Reactivation Theory of Implicit Memory

Implicit and explicit memory tasks are interpreted within a traditional memory theory that distinguishes associations between different classes of memory units (sensory features, logogens, imagens, concepts, context tags). Associations from specific sensory features to logogens are strengthened by perceptual experiences, leading to specific perceptual priming. Associations among concepts are st...